Surgical Indications in Hashimoto’s Thyroiditis: A Retrospective Study from Tobruk Medical Center
- Authors
-
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Faraj Aljali
General Surgery Department, Faculty of Medicine, Tobruk University, Tobruk, LibyaAuthor -
Fathi Asnini
General Surgery Department, Faculty of Medicine, Tobruk University, Tobruk, LibyaAuthor
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- Keywords:
- Hashimoto’s Thyroiditis, Thyroidectomy, Surgical Indications, anti-TPO, Goiter
- Abstract
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Hashimoto’s thyroiditis (HT) is the most common cause of hypothyroidism and an autoimmune disorder characterized by chronic inflammation of the thyroid gland. While most patients are managed medically, a subset requires surgical intervention. This study was conducted to identify the clinical, laboratory, and radiological indications for surgery in patients with Hashimoto’s thyroiditis. A retrospective analysis of 63 patients diagnosed with HT between January 2010 and December 2021 at Tobruk Medical Center. Data included clinical presentation, thyroid function tests (T3, T4, TSH), autoantibodies (Anti-TPO, Anti-TG), ultrasound findings, and fine needle aspiration cytology (FNAC). Statistical analysis was performed using the Chi-square test (SPSS 23). Of 63 patients, 51 (80.9%) were treated medically and 12 (19.1%) surgically. Significant associations with surgical treatment were found for age <40 years (p<0.05), female sex (p<0.05), positive family history (p<0.05), diagnostic ultrasound findings (p<0.05), and informative FNAC (p<0.05). Hypothyroidism was present in 57.2%, euthyroidism in 39.6%, and hyperthyroidism in 3.2%. All patients were Anti-TPO positive, and 58.7% were Anti-TG positive. Surgery for Hashimoto’s thyroiditis is indicated in patients with compressive goiter, persistent high autoantibody levels despite medical therapy, or thyroid nodules with suspected or confirmed malignancy.
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- Published
- 2026-04-29
- Section
- Articles
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