Antibacterial Activity, Phytochemical Screening, and Chemical Profiling of Leaves and Stems of the Rubia Plant

• Hamad Hasan

  Chemistry Department, Faculty of Science, Omar Al-Mukhtar University, Libya

  Author

• Fatimah Abdulsayid

  Chemistry Department, Faculty of Science, Alkufra University, Libya

  Author

• Boodor Alshareef

  Botany Department, Faculty of Science, AlKufra University, Libya

  Author

• Salem Mahmoud

  Chemistry Department, Faculty of Science, Omar Al-Mukhtar University, Libya

  Author

• Zuhir Ikrim

  Pharmacology and Toxicology Department, Pharmacy Faculty, Omar Al-Muktar University, Libya

  Author

• Salha Sergewa

  Chemistry Department, Faculty of Science, Derna University, Libya

  Author

Plants as medicines have been used for thousands of years. Herbal extracts and formulations have long been regarded as a source of new and useful pharmaceuticals. The chemical composition of plant-based medicines has become a new interest these days. Several bioactive constituents of plants have been isolated and studied for various pharmacological studies. Rubia species are one of the earliest plant resources that possess commercial and important medicinal values. They were used as natural dyes in the old days and as drugs. The leaves and stems of Rubia plant were collected from Ain-Mara and Ras-Elhelal in the Al-Gabel Al –Kadar region during spring season of (2024) The results of phytochemical screening of aqueous and methanolic extracts of leaves and stems of Rubia plants showed absence of Anthraquinone in the two extracts, the Rubia leaves contain higher amount of total carbohydrates, amino acids, total protein, total phenols and antioxidant activity compared to Rubia stems, The anti-bacterial activity  (mm) of aqueous extracts of Rubia leaves and stems did not appear any inhibition zones for E coli.

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